Advancing quantitative proteomics: strategies for accurate protein analysis

Research theses
Abstract

This project explores advanced strategies for the quantitative analysis of proteins, a central challenge in modern proteomics. The work will focus on understanding and improving the accuracy and reliability of protein quantification by systematically evaluating current analytical and proteolytic approaches. Through a combination of experimental work and data analysis, the student will investigate how methodological choices impact quantitative results in complex biological systems. The project sits at the interface of analytical biochemistry and proteomics, offering interdisciplinary training in method development, critical evaluation, and protein characterization.

The student will join an interdisciplinary research environment and work closely with the supervisor on a focused research project. The internship offers training in analytical biochemistry and proteomics, with opportunities to engage in scientific discussions and, when possible, attend scientific meetings. Highly motivated students are encouraged to apply. The position is based in Santander, a vibrant coastal city in northern Spain.

Keywords
Quantitative proteomics
Protein quantification
Analytical strategies
Proteolysis
Method development
ERC sector(s)
LS Life Sciences
Thesis supervisor
Name supervisor
Francisco Calderón Celis
E-mail
eunice@unican.es
Department/Faculty/School/Institute/Area/Division NAME
Instituto de Biomedicina y Biotecnología de Cantabria (IBBTEC)
Name of the host University
University of Cantabria (UC)
EUNICE partner e-mail of destination Research
area.eunice@unican.es
Country
Spain
Student profile
Thesis level
Bachelor
Master
Minimal language knowledge requisite
English B2
Additional info
Length of the research internship
3 months
Financial support available (other than E+)
No
Research interests for cooperation opportunities
Analytical biochemistry focused on developing advanced strategies for accurate and reliable quantitative analysis of proteins and their post-translational modifications.